Weight loss surgery reduces the risk of cancer and mortality in obese people

According to a new study, people who are obese are twice as likely to develop cancer and 3.5 times more likely to die from it than those who have undergone weight loss surgery.

According to the Centers for Disease Control and Prevention, 41.9% of adults in the United States are obese and 9.2% are severely obese. Obesity contributes to a wide range of health problems, including cancer. In fact, according to the CDC, being overweight or obese is associated with a higher risk of developing 13 different types of cancer.

People who are severely obese and have problems with weight loss sometimes resort to weight loss surgery. Two common types nowadays are gastric bypass surgery and gastric bypass surgery. When the stomach is bypassed, the upper part of the stomach turns into a small sac and connects with the small intestine further down. This bypasses your stomach, reducing calories absorbed. At a sleeve resection of a stomach approximately 80% of a stomach therefore there is a tubular stomach similar in the size and the form to a banana is removed.

Obese people were at least twice as likely to develop certain types of cancer and 3.5 times more likely to die from the disease than those who underwent weight loss surgery, according to a new study released today (June 7, 2022). ) Annual Meeting of the American Society for Metabolic and Bariatric Surgery (ASMBS) (# ASMBS2022).

The researchers found that after weight loss surgery, patients reported a significant reduction in breast cancer (1.4% vs. 2.7%), gynecological cancer (0.4% vs. 2.6%), kidney cancer (0.10 % vs. 0.80%), brain cancer. cancer (0.20% vs. 0.90%), lung cancer (0.20% vs. 0.60%), and thyroid cancer (0.10% vs. 0.70%).

The 10-year incidence of any new cancer in the bariatric group was significantly lower (5.2% vs. 12.2%), and the 10-year survival rate was significantly higher (92.9% vs. 78.9%) than in the non-surgical group. . The retrospective study included 1,620 patients who underwent gastric bypass surgery (1,265 patients) or manual gastrectomy (355 patients) between September 2001 and December 2019, and 2,156 patients selected based on age, sex, and weight index. body (BMI) who did not do surgery. The researchers estimated that patients lost about 60% of their excess weight after surgery in 10 years.

“We knew that bariatric surgery would reduce the risk of cancer based on previous research, but what surprised us was the extent of this reduction in some cancers,” said study co-author Jared R. Miller, MD, general and bariatric surgeon. in Gundersen Lutheran Health Care System. “The benefits of reducing cancer risk through weight loss surgery cannot be ignored and should be considered by patients with obesity and a high risk of cancer.”

The US Centers for Disease Control and Prevention (CDC) estimates that there are more than 650,000 obesity-related cancers in the United States each year. From 2005 to 2014, most cancers related to overweight and obesity increased by 7%, while the number of new cancers related to overweight decreased by 13%. According to American Society of Clinical Oncology (ASCO)Obesity is a major unrecognized risk factor for cancer and is associated with worsening prognosis after cancer diagnosis.

Being overweight and obese can cause changes in the body that can lead to cancer, including prolonged inflammation and high insulin levels. The the risk of cancer increases the more overweight a person gains and the longer he is overweight or obese.

“The data continues to grow – if you treat obesity, you prevent some cancers,” said Shanu Kotari, MD, president of ASMBS, who was not involved in the study. “Weight loss surgery has proven to be the most effective long-term treatment for obesity, and it is now increasingly seen as a preventative treatment not only for cancer but also for heart disease, stroke and type 2 diabetes.”

In 2016, ASMBS released Fr. statement of position about the relationship between obesity and cancer, and the role of bariatric surgery and the impact of weight loss not only on cancer risk but also on post-treatment survival.

Reference: “Cancer, type and survival after bariatric surgery” by Jared R. Miller, MD, Alec J. Fitzsimans, Ph.D., Andrew J. Borgert, Ph.D., Caitlin M. Melion, MD, Joshua D. Pfeiffer, MD and Brendan T. Grover, DO, FACS, June 7, 2022, Annual Meeting of the American Society for Metabolic and Bariatric Surgery.

About weight loss surgery

Metabolic / bariatric surgeries or weight loss surgeries, such as gastric bypass and gastric bypass, have proven to be the most effective and long-lasting treatments for severe obesity. Surgery improves or resolves diseases including type 2 diabetes, heart disease and high blood pressure, and leads to significant and lasting weight loss. His the safety profile is comparable to some of the safest and most commonly performed surgeries in the U.S., including gallbladder surgery, appendectomy, and knee replacement. Weight loss surgery is usually designed for people who are severely obese, which means about 75 to 100 pounds of overweight or a BMI of 35 or higher with an obesity-related disease. Obesity is associated with early death and more than 40 diseases, including type 2 diabetes, hypertension, heart disease, stroke, osteoarthritis and at least 13 different types of cancer.[1],[2],[3] According to the ASMBS, less than 1% of those eligible for weight loss surgery perform it in any year – in 2019, according to the latest available estimates, about 256,000 bariatric surgeries were performed.


  1. Efficacy and risks of bariatric surgery: an updated systematic review and meta-analysis, 2003-2012. DOI: 10.1001 / jamasurg.2013.3654
  2. Style CB, Thomas CC, Henley SJ et al. Signs of life: trends in cancer associated with overweight and obesity – USA, 2005-2014. MMWR Morb Mortal Wkly Rep 2017; 66: 1052–1058. DOI: 10.15585 / mmwr.mm6639e1
  3. Centers for Disease Control and Prevention. (2015) The impact of overweight and obesity on health. Accessed from:


ASMBS is the largest organization of bariatric surgeons in the country. It is a non-profit organization that promotes the art and science of bariatric surgery and seeks to educate health professionals and non-professionals about bariatric surgery as an option for treating severe obesity, as well as the associated risks and benefits. . It encourages its members to explore and discover new advances in bariatric surgery by supporting a sustained exchange of experiences and ideas that can lead to improved surgical outcomes for severely obese patients. Weight loss surgery reduces the risk of cancer and mortality in obese people

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