The latest research on the risks of coffee and heart rhythm problems – good news

UCSF cardiology researchers report that there is no link between coffee consumption and arrhythmias.

In the largest study of its kind, a study by the University of California, San Francisco found no evidence that moderate coffee consumption could cause cardiac arrhythmias.

In fact, for every cup of coffee that hundreds of thousands of individuals drink each day, researchers say that the risk of developing arrhythmias such as atrial fibrillation, premature ventricular contractions, and other common heart diseases is reduced by 3%. Is reporting. This study included a 4-year follow-up.

This treatise was published on July 19, 2021. JAMA Internal Medicine..

“Coffee is a major source of caffeine for most people and has a reputation for causing and exacerbating arrhythmias,” said a senior responding author, a professor of medicine at the University of California, San Francisco School of Cardiology. One Gregory Marcus Medical Doctor said.

“But we didn’t find any evidence that caffeine intake increases the risk of arrhythmias,” said Marcus, who specializes in the treatment of arrhythmias. “Our population-based studies provide peace of mind that a general ban on caffeine to reduce the risk of arrhythmias is probably unreasonable.”

Some expert associations have suggested avoiding caffeine products to reduce the risk of arrhythmias, but this relationship has not been consistently demonstrated. In fact, coffee consumption has anti-inflammatory effects and is associated with a reduced risk of several illnesses such as cancer, diabetes and Parkinson’s disease. ..

In a new study, UCSF scientists investigated whether habitual coffee consumption was associated with the risk of arrhythmias, and whether genetic variation affecting caffeine metabolism could alter that association. Their study was conducted through the community-based UK Biobank, a prospective study of participants in the UK National Health Service.

About 386,258 coffee drinkers participated in the coffee study, with an average age of 56 years. Over half were women. This type of study had an unprecedented sample size.

In addition to traditional analysis of self-reported coffee consumption as a predictor of future arrhythmias, researchers have adopted a technique called “Mendel’s laws” to infer causal relationships using genetic data. This analysis is independent of participants’ self-reports and should be unaffected by many confounding-specific methods, as people with genetic variation associated with faster caffeine metabolism drank more coffee. Provided a way to test the relationship between caffeine and arrhythmias in most observational studies.

With an average of four years of follow-up, the data were tailored to demographic characteristics, health, and lifestyle habits.

Eventually, about 4% of the samples developed arrhythmias. No evidence of an increased risk of arrhythmia was observed among individuals with a genetic predisposition to metabolize caffeine differently. Researchers say that the higher the amount of coffee, the lower the risk of actually developing an arrhythmia by 3%.

The authors pointed out that no detailed information was available on restrictions, including the nature of the study’s self-report, and the type of coffee (such as espresso or not).

“Only randomized clinical trials can clearly show the clear effects of coffee and caffeine intake,” says Marcus. “But our study found no evidence that caffeinated beverages increase the risk of arrhythmias. The antioxidant and anti-inflammatory effects of coffee may play a role in caffeine. Some properties may prevent some arrhythmias. “

Reference: “Coffee consumption and reported behavior of accidental tachyarrhythmias, Mendelian randomization, and their interactions” by Dr. Kim Eun-jung.Dr. Thomas J. Hoffman; Gregory, Massachusetts; Dr. Eric Wittinhof; Francesca Delling, MD and Gregory M. Marcus, MD, MAS, July 19, 2021 JAMA Internal Medicine..
DOI: 10.1001 / jamainternmed.2021.3616

The co-author is Dr. Kim Eun-jung, MD. Dr. Thomas J. Hoffman; Gregolina, Massachusetts; Dr. Eric Wittinhof; and Francesca Delling, MD, All UCSF. The latest research on the risks of coffee and heart rhythm problems – good news

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